Double-Charge Detector 0341U

Ftl aneup dna seq cmpr alys — 112 bundling rules

If your bill lists 0341U alongside any of these codes as separate charges, it may be an unbundling error.

By Michael Glenn , Healthcare Data Analyst · Published March 15, 2026 · Updated April 3, 2026

About the analyst

Michael Glenn reviews CMS datasets and drug pricing at BillRazor Research. He focuses on NADAC acquisition costs and procedure coding accuracy. Expertise: drug pricing, NADAC data, CPT coding.

NCCI edit data

112 code pairs

Updated 2026-04-03

Bundling rules — 0341U

NCCI edits: these codes have billing restrictions when billed with 0341U

Research suggests 49–80% of hospital bills contain errors. Our system checks every line item against Medicare benchmarks.

Common unbundling errors — medical procedures

Unbundling occurs when medical providers bill two separate codes for services that should be combined into a single charge according to National Correct Coding Initiative (NCCI) rules. In other procedures including anesthesia, radiology, pathology, and miscellaneous support services, common unbundling patterns include separately billing diagnostic imaging with its professional interpretation when both should be included in one comprehensive code, and charging for basic monitoring or preparation services alongside the primary procedure when these components are considered integral parts of the main service. Another frequent error involves billing multiple pathology examination codes for what constitutes a single comprehensive analysis. With 809 other codes subject to bundling restrictions in the NCCI database, these errors create charges above the benchmark for patients who receive multiple bills for what should constitute one complete service. The potential difference between unbundled billing and correct coding practices can significantly impact patient financial responsibility, as they may face duplicate charges for components of care that medical coding standards define as a single billable service.

What to check on your bill

When reviewing itemized bills for procedure bundling issues, patients should examine several key areas to identify potential billing irregularities. Look for multiple procedure codes billed on the same date that represent components of a comprehensive service, such as separate charges for incision, repair, and closure when these steps are typically included in one primary procedure code. Watch for code patterns where related procedures share the same first three digits, as these often indicate services that should be bundled together under Medicare's Correct Coding Initiative. Check for appropriate modifier usage, particularly modifier 59 or XS, which legitimately allow separate billing when procedures are performed on different anatomical sites or during distinct sessions. Without proper modifiers, separately billed related procedures may represent charges above the benchmark. Compare your itemized statement against standard bundling practices for your specific procedure type to identify potential differences in billing patterns.

All bundling rules for 0341U

112 code pairs that have billing restrictions with this procedure.

Never bill together

111

May bill with modifier

Code	Description	Rule
0068U	Candida species pnl amp prb	May bill with modifier
0112U	Iadi 16s&18s rrna genes	May bill with modifier
0115U	Respir iadna 18 viral&2 bact	May bill with modifier
0202U	Nfct ds 22 trgt sars-cov-2	May bill with modifier
0252U	Ftl aneuploidy str alys dna	Never bill together
0403U	Onc prst8 mrna 18 gen 1st ur	May bill with modifier
0410U	Onc pncrtc dna whl gn seq 5-	May bill with modifier
0414U	Onc lng aug alg aly whl sld8	May bill with modifier
0418U	Onc brst aug alg aly whl sl8	May bill with modifier
0429U	Hpv orop swab 14 hi-risk typ	May bill with modifier
81513	Nfct ds bv rna vag flu alg	May bill with modifier
84311	Spectrophotometry	May bill with modifier
87140	Culture type immunofluoresc	May bill with modifier
87143	Culture typing glc/hplc	May bill with modifier
87147	Culture type immunologic	May bill with modifier
87149	Dna/rna direct probe	May bill with modifier
87150	Dna/rna amplified probe	May bill with modifier
87152	Culture type pulse field gel	May bill with modifier
87153	Dna/rna sequencing	May bill with modifier
87158	Culture typing added method	May bill with modifier
87471	Bartonella dna amp probe	May bill with modifier
87472	Bartonella dna quant	May bill with modifier
87475	Lyme dis dna dir probe	May bill with modifier
87476	Lyme dis dna amp probe	May bill with modifier
87480	Candida dna dir probe	May bill with modifier
87481	Candida dna amp probe	May bill with modifier
87482	Candida dna quant	May bill with modifier
87483	Cns dna amp probe type 12-25	May bill with modifier
87485	Chlmyd pneum dna dir probe	May bill with modifier
87486	Chlmyd pneum dna amp probe	May bill with modifier
87487	Chlmyd pneum dna quant	May bill with modifier
87490	Chlmyd trach dna dir probe	May bill with modifier
87491	Chlmyd trach dna amp probe	May bill with modifier
87492	Chlmyd trach dna quant	May bill with modifier
87493	C diff amplified probe	May bill with modifier
87495	Cytomeg dna dir probe	May bill with modifier
87496	Cytomeg dna amp probe	May bill with modifier
87497	Cytomeg dna quant	May bill with modifier
87498	Enterovirus probe&revrs trns	May bill with modifier
87500	Vanomycin dna amp probe	May bill with modifier
87501	Influenza dna amp prob 1+	May bill with modifier
87502	Influenza dna amp probe	May bill with modifier
87503	Influenza dna amp prob addl	May bill with modifier
87505	Nfct agent detection gi	May bill with modifier
87506	Iadna-dna/rna probe tq 6-11	May bill with modifier
87507	Iadna-dna/rna probe tq 12-25	May bill with modifier
87510	Gardner vag dna dir probe	May bill with modifier
87511	Gardner vag dna amp probe	May bill with modifier
87512	Gardner vag dna quant	May bill with modifier
87516	Hepatitis b dna amp probe	May bill with modifier

Showing 50 of 112 rules. Show all

FAQ — medical procedure bundling

What is NCCI bundling and what does 'bundled' mean on a medical bill?

NCCI bundling refers to the National Correct Coding Initiative rules that prevent certain procedure codes from being billed separately when performed together. When codes are bundled, one procedure is considered inclusive of another, meaning only the primary procedure should be billed rather than charging for each component separately.

How can I identify if codes were incorrectly unbundled on my bill?

Incorrectly unbundled codes appear as separate line items on your bill when NCCI rules indicate they should be grouped together under one primary procedure code. This typically occurs with anesthesia, radiology, pathology, and miscellaneous support services that are considered integral to the main procedure being performed.

What should I do if I find unbundled charges on my medical bill?

Contact your healthcare provider's billing department to request a review of the charges and provide documentation showing the NCCI bundling rules that apply. Request an itemized explanation of why the codes were billed separately and ask for a corrected bill that reflects proper bundling if no valid modifier justification exists.

When is it legitimate to use modifiers to override NCCI bundling rules?

Modifiers are appropriately used when procedures are performed on different anatomical sites, during separate patient encounters, or when distinct procedural services are provided that don't fall under the bundling restrictions. The modifier usage must be supported by clear documentation in the medical record that demonstrates the services were truly separate and distinct from the bundled procedure.

Rates shown are from the 2026 Medicare Physician Fee Schedule and CMS IPPS. BillRazor compares your bill against these data sources. See how it works →

Data source: CMS National Correct Coding Initiative (NCCI) Procedure-to-Procedure (PTP) edits, updated quarterly. These code pairs are maintained by CMS to prevent improper billing of services that should be billed as a single procedure.

What this means: When two codes are listed as an NCCI edit pair, billing them separately on the same date of service is typically incorrect. "Never bill together" means no modifier can override the rule. "May bill with modifier" means the codes can be billed separately with appropriate documentation.