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Double-Charge Detector 0475U

Hered prst8 ca gsap 23 genes — 78 bundling rules

If your bill lists 0475U alongside any of these codes as separate charges, it may be an unbundling error.

By Elena Vasquez , Medical Billing Research Lead · ·
About the analyst

Elena Vasquez leads hospital billing pattern analysis at BillRazor Research. She focuses on identifying overcharges, markup outliers, and patient advocacy strategies. Expertise: hospital billing patterns, overcharge analysis, patient advocacy.

NCCI edit data
78 code pairs
Updated 2026-04-03
Bundling rules — 0475U
NCCI edits: these codes have billing restrictions when billed with 0475U
0475U0005UOnco prst8 3 gene ur algNever bill together0011MOnc prst8 ca mrna 12 gen algNever bill together0021UOnc prst8 detcj 8 autoantbNever bill together0113UOnc prst8 pca3&tmprss2-ergNever bill together0228UOnc prst8 ma molec prfl algNever bill together0339UOnc prst8 mrna hoxc6 & dlx1May bill with modifier0343UOnc prst8 xom aly 442 sncrnaMay bill with modifier0359UOnc prst8 ca alys all psaMay bill with modifier
Research suggests 49–80% of hospital bills contain errors. Our system checks every line item against Medicare benchmarks.

Common unbundling errors — medical procedures

Unbundling occurs when medical providers bill two separate codes for services that should be combined into a single charge according to National Correct Coding Initiative (NCCI) rules. In other procedures including anesthesia, radiology, pathology, and miscellaneous support services, common unbundling patterns include separately billing diagnostic imaging with its professional interpretation when both should be included in one comprehensive code, and charging for basic monitoring or preparation services alongside the primary procedure when these components are considered integral parts of the main service. Another frequent error involves billing multiple pathology examination codes for what constitutes a single comprehensive analysis. With 809 other codes subject to bundling restrictions in the NCCI database, these errors create charges above the benchmark for patients who receive multiple bills for what should constitute one complete service. The potential difference between unbundled billing and correct coding practices can significantly impact patient financial responsibility, as they may face duplicate charges for components of care that medical coding standards define as a single billable service.

What to check on your bill

When reviewing itemized bills for procedure bundling issues, patients should examine several key areas to identify potential billing irregularities. Look for multiple procedure codes billed on the same date that represent components of a comprehensive service, such as separate charges for incision, repair, and closure when these steps are typically included in one primary procedure code. Watch for code patterns where related procedures share the same first three digits, as these often indicate services that should be bundled together under Medicare's Correct Coding Initiative. Check for appropriate modifier usage, particularly modifier 59 or XS, which legitimately allow separate billing when procedures are performed on different anatomical sites or during distinct sessions. Without proper modifiers, separately billed related procedures may represent charges above the benchmark. Compare your itemized statement against standard bundling practices for your specific procedure type to identify potential differences in billing patterns.

All bundling rules for 0475U

78 code pairs that have billing restrictions with this procedure.

9
Never bill together
69
May bill with modifier
Code Description Rule
0005U Onco prst8 3 gene ur alg Never bill together
0011M Onc prst8 ca mrna 12 gen alg Never bill together
0021U Onc prst8 detcj 8 autoantb Never bill together
0113U Onc prst8 pca3&tmprss2-erg Never bill together
0228U Onc prst8 ma molec prfl alg Never bill together
0339U Onc prst8 mrna hoxc6 & dlx1 May bill with modifier
0343U Onc prst8 xom aly 442 sncrna May bill with modifier
0359U Onc prst8 ca alys all psa May bill with modifier
0403U Onc prst8 mrna 18 gen 1st ur May bill with modifier
0424U Onc prst8 xom alys 53 sncrna May bill with modifier
0433U Onc prst8 5 dna reg mrk pcr May bill with modifier
0495U Onc prst8 alys crcg plsm prt May bill with modifier
36591 Draw blood off venous device Never bill together
36592 Collect blood from picc Never bill together
80503 Path clin consltj sf 5-20 May bill with modifier
80504 Path clin consltj mod 21-40 May bill with modifier
80505 Path clin consltj high 41-60 May bill with modifier
81170 Abl1 gene May bill with modifier
81191 Ntrk1 translocation analysis May bill with modifier
81192 Ntrk2 translocation analysis May bill with modifier
81193 Ntrk3 translocation analysis May bill with modifier
81194 Ntrk translocation analysis May bill with modifier
81210 Braf gene May bill with modifier
81228 Cytog alys chrml abnr cgh May bill with modifier
81229 Cytog alys chrml abnr snpcgh May bill with modifier
81232 Dpyd gene common variants May bill with modifier
81235 Egfr gene com variants May bill with modifier
81275 Kras gene variants exon 2 May bill with modifier
81292 Mlh1 gene full seq May bill with modifier
81293 Mlh1 gene known variants May bill with modifier
81294 Mlh1 gene dup/delete variant May bill with modifier
81295 Msh2 gene full seq May bill with modifier
81296 Msh2 gene known variants May bill with modifier
81297 Msh2 gene dup/delete variant May bill with modifier
81298 Msh6 gene full seq May bill with modifier
81299 Msh6 gene known variants May bill with modifier
81300 Msh6 gene dup/delete variant May bill with modifier
81301 Microsatellite instability May bill with modifier
81307 Palb2 gene full gene seq May bill with modifier
81308 Palb2 gene known famil vrnt May bill with modifier
81311 Nras gene variants exon 2&3 May bill with modifier
81313 Pca3/klk3 antigen May bill with modifier
81317 Pms2 gene full seq analysis May bill with modifier
81318 Pms2 known familial variants May bill with modifier
81319 Pms2 gene dup/delet variants May bill with modifier
81327 Sept9 gen prmtr mthyltn alys May bill with modifier
81346 Tyms gene com variants May bill with modifier
81351 Tp53 gene full gene sequence May bill with modifier
81352 Tp53 gene trgt sequence alys May bill with modifier
81353 Tp53 gene known famil vrnt May bill with modifier

Showing 50 of 78 rules. Show all

FAQ — medical procedure bundling

What is NCCI bundling and what does 'bundled' mean on a medical bill?
NCCI bundling refers to the National Correct Coding Initiative rules that prevent certain procedure codes from being billed separately when performed together. When codes are bundled, one procedure is considered inclusive of another, meaning only the primary procedure should be billed rather than charging for each component separately.
How can I identify if codes were incorrectly unbundled on my bill?
Incorrectly unbundled codes appear as separate line items on your bill when NCCI rules indicate they should be grouped together under one primary procedure code. This typically occurs with anesthesia, radiology, pathology, and miscellaneous support services that are considered integral to the main procedure being performed.
What should I do if I find unbundled charges on my medical bill?
Contact your healthcare provider's billing department to request a review of the charges and provide documentation showing the NCCI bundling rules that apply. Request an itemized explanation of why the codes were billed separately and ask for a corrected bill that reflects proper bundling if no valid modifier justification exists.
When is it legitimate to use modifiers to override NCCI bundling rules?
Modifiers are appropriately used when procedures are performed on different anatomical sites, during separate patient encounters, or when distinct procedural services are provided that don't fall under the bundling restrictions. The modifier usage must be supported by clear documentation in the medical record that demonstrates the services were truly separate and distinct from the bundled procedure.
Rates shown are from the 2026 Medicare Physician Fee Schedule and CMS IPPS. BillRazor compares your bill against these data sources. See how it works →

Data source: CMS National Correct Coding Initiative (NCCI) Procedure-to-Procedure (PTP) edits, updated quarterly. These code pairs are maintained by CMS to prevent improper billing of services that should be billed as a single procedure.

What this means: When two codes are listed as an NCCI edit pair, billing them separately on the same date of service is typically incorrect. "Never bill together" means no modifier can override the rule. "May bill with modifier" means the codes can be billed separately with appropriate documentation.

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