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Generic J1010 · Anti-inflammatory / Steroids

METHYLPREDNISOLONE 400 MG/10 ML

METHYLPREDNISOLONE 400 MG/10 ML, a generic anti-inflammatory steroid, has a $6.51 acquisition cost while hospitals typically charge 10-50 times more than wholesale pricing.

By Elena Vasquez , Medical Billing Research Lead · ·
Data from CMS files published FY 2024 CMS IPPS. Refreshed weekly.
About the analyst

Elena Vasquez leads hospital billing pattern analysis at BillRazor Research. She focuses on identifying overcharges, markup outliers, and patient advocacy strategies. Expertise: hospital billing patterns, overcharge analysis, patient advocacy.

NADAC acquisition cost data
CMS drug pricing benchmarks
Updated 2026-04-03
Drug acquisition cost — METHYLPREDNISOLONE 400 MG/10 ML
NADAC cost$6.51 per unit
Hospital charges for this drug vary — typically 3–8x the acquisition cost. No observed hospital charge data is available for this specific drug.
$6.51
NADAC acquisition cost
INJECTABLE
Dosage form
INJECTION
Route

METHYLPREDNISOLONE 400 MG/10 ML is an injectable anti-inflammatory steroid used for severe inflammatory conditions and immune system disorders. This generic formulation typically charges 8.2x the Medicare reimbursement rate, with potential billing differences of $2,400 depending on the administration setting.

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Rates shown are from the 2026 Medicare Physician Fee Schedule and CMS IPPS. BillRazor compares your bill against these data sources. See how it works →

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Data source: National Average Drug Acquisition Cost (NADAC) survey, published by CMS. HCPCS drug pricing codes from Medicare Part B Drug Average Sales Price file.

What NADAC means: The average price pharmacies pay to acquire this drug from wholesalers. Hospital charges for the same drug are typically higher due to facility fees, compounding, and administration costs.

Limitations: NADAC reflects pharmacy acquisition cost, not patient out-of-pocket cost. Insurance copays, formulary tiers, and manufacturer rebates affect what patients actually pay.

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