Generic J2550

PROMETHAZINE 50 MG/ML AMPUL

PROMETHAZINE 50 MG/ML AMPUL, a generic medication with an acquisition cost of $2.36, typically shows significant pricing variation between acquisition cost and hospital billing rates.

By David Park , Healthcare Cost Researcher · Published March 15, 2026 · Updated April 3, 2026

Data from CMS files published FY 2024 CMS IPPS. Refreshed weekly.

About the analyst

David Park researches procedure pricing and insurance reimbursement patterns at BillRazor Research. He specializes in cost comparison across care settings and metropolitan areas. Expertise: procedure pricing, insurance reimbursement, cost comparison.

NADAC acquisition cost data

CMS drug pricing benchmarks

Updated 2026-04-03

Drug acquisition cost — PROMETHAZINE 50 MG/ML AMPUL

Hospital charges for this drug vary — typically 3–8x the acquisition cost. No observed hospital charge data is available for this specific drug.

$2.36

NADAC acquisition cost

INJECTABLE

Dosage form

INJECTION

Route

Promethazine 50 mg/ml ampules are used for treating nausea, vomiting, and allergic reactions in hospital settings. Injectable formulations typically generate higher reimbursement rates compared to oral alternatives, with potential billing differences of several hundred dollars depending on administration setting.

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Data source: National Average Drug Acquisition Cost (NADAC) survey, published by CMS. HCPCS drug pricing codes from Medicare Part B Drug Average Sales Price file.

What NADAC means: The average price pharmacies pay to acquire this drug from wholesalers. Hospital charges for the same drug are typically higher due to facility fees, compounding, and administration costs.

Limitations: NADAC reflects pharmacy acquisition cost, not patient out-of-pocket cost. Insurance copays, formulary tiers, and manufacturer rebates affect what patients actually pay.