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Cost Guide 84166 · Pathology/Lab

How much does Protein separation test from urine or spinal fluid cost?

Medicare pays $17.

By Priya Iyengar , Senior Billing Analyst · ·
Data from CMS files published FY 2024 CMS IPPS. Refreshed weekly.
About the analyst

Priya Iyengar leads the billing code review team at BillRazor Research. She analyzes NCCI bundling edits, DRG coding, and regional rate variation. Expertise: NCCI bundling, DRG analysis, regional pricing.

3 care settings compared
CMS Medicare benchmark data
Updated 2026-04-03
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$18
Medicare rate
$71
Price spread
Rate comparison — Protein separation test from urine or spinal fluid
Medicare facility$18Non-facility$99$81 difference between lowest and highest rate
Research suggests 49–80% of hospital bills contain errors. Our system checks every line item against Medicare benchmarks.

Cost by care setting

Setting Medicare rate
Hospital outpatient (facility) $18
Physician office (non-facility) $99
Clinical laboratory $18

What affects the cost?

How to save on Protein separation test from urine or spinal fluid

  • 1 Ask your doctor to use a preferred lab network
  • 2 Request a cost estimate before the test is run
  • 3 Check if a less expensive alternative test exists
Rates shown are from the 2026 Medicare Physician Fee Schedule and CMS IPPS. BillRazor compares your bill against these data sources. See how it works →

FAQ — Protein separation test from urine or spinal fluid cost

What is a fair price for Protein e-phoresis/urine/csf?
Medicare pays $17 for Protein e-phoresis/urine/csf (84166). This is the government benchmark rate. A fair price for commercially insured or cash-pay patients is typically 1.2–2.5x the Medicare rate, or roughly $21–$44.
How can I lower my cost for Protein e-phoresis/urine/csf?
To lower your cost: (1) Compare prices at multiple facilities — use the comparison data on this page. (2) Ask about ASC (surgery center) options, which are often 40–60% cheaper. (3) Request cash-pay pricing upfront. (4) After receiving a bill, review each line item against Medicare benchmarks. Research suggests 49–80% of hospital bills contain errors.

Related pricing data

Protein separation test from urine or spinal fluid — Medicare rate detailsFull Medicare rate breakdown by setting and locality
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Data: Federal physician fee schedules, hospital payment data, surgery center rates, lab fee schedules, and drug pricing data. FY 2024. All publicly available from federal sources.

Methodology: Rates shown are national Medicare reimbursement rates by care setting. Price ranges reflect variation across hospitals reporting the same procedure code. Metro prices are averaged from hospital-level chargemaster data reported to CMS.

This information is for educational purposes only and is not medical, financial, or legal advice. Actual costs depend on your insurance and provider. We recommend verifying costs directly with your provider. Full methodology · Terms of use

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