Pild/placebo control clin tr
Clinical trial participation costs range from $360.51 to $7,143.73 depending on your facility type, with hospitals charging 19.8x the Medicare benchmark—verify your bill immediately.
About the analyst
Kevin Nyk analyzes hospital pricing data at BillRazor Research. He specializes in Medicare reimbursement patterns and chargemaster pricing across U.S. hospitals. Expertise: hospital pricing, Medicare rates, chargemaster analysis.
Code G0276 covers billing for patient participation in qualifying clinical trials, either receiving the experimental treatment or placebo as part of FDA-approved research studies. Cancer patients and those with chronic conditions often participate when standard treatments have limited effectiveness. Medicare typically covers routine care costs associated with approved clinical trials, but billing requires specific documentation to distinguish trial-related services from standard care.
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Common billing errors
When reviewing Procedures & Services bills for temporary procedures, watch for several common billing patterns. Duplicate charges frequently occur when the same temporary procedure code appears multiple times within a single date of service, particularly with monitoring or observational codes that should be billed once per session. Unbundling errors are common when temporary diagnostic procedures are separated into component parts rather than using the appropriate comprehensive code, creating charges above the benchmark rates. Code confusion often happens between similar temporary procedure codes with significantly different Medicare rates - some procedures are valued at $0 while others reach $1,363, making accurate code selection critical. Additionally, verify that temporary procedures aren't billed alongside permanent procedure codes for the same service area on the same date, as this creates inappropriate dual billing. Given the wide rate variation in this 227-code category, confirm that the specific temporary procedure code matches the actual service provided and duration documented in your medical records.
Facility rate
$361
National Medicare benchmark
Non-facility rate
$99
Office setting benchmark
Data sources
4
24 data points
Key insights for HCPCS G0276
ASC vs hospital outpatient savings
$3,633Having this done at an ambulatory surgery center costs $3,511 vs $7,144 at a hospital outpatient
Facility vs office setting
$262 differenceNon-facility setting is less expensive for this procedure
What this procedure costs across different settings
The same procedure can cost very different amounts depending on where it's performed. These are the Medicare-allowed amounts — what hospitals actually charge can be 3-10x higher.
| Setting | Medicare rate | vs lowest |
|---|---|---|
| Facility (physician office) | $361 | +264% |
| Non-facility (office) | $99 | Lowest |
| Outpatient (APC) | $7,144 | +7116% |
| Ambulatory surgery (ASC) | $3,511 | +3446% |
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About this data
Rates shown are from the 2026 Medicare Physician Fee Schedule, Hospital Outpatient Prospective Payment System (OPPS), Ambulatory Surgery Center Payment System, Clinical Laboratory Fee Schedule, Durable Medical Equipment Fee Schedule, and CMS Inpatient Prospective Payment System (DRG weights). Regional adjustments use CMS Geographic Practice Cost Indices (GPCI). Hospital charges are from CMS Hospital Price Transparency machine-readable files. All data is publicly available under federal law (45 CFR Part 180).
This data is for informational purposes only and does not constitute medical or financial advice. Actual costs depend on insurance coverage, negotiated rates, and individual circumstances.
Related procedures
FAQ — Temporary Procedures & Services billing
What is the Medicare reimbursement range for Temporary Procedures & Services?
How should I verify appropriate billing rates for temporary procedures?
Why do some temporary procedures have a $0 Medicare rate?
What billing considerations apply to the temporary procedure category?
Related pricing data
Data: Medicare Physician Fee Schedule, CMS Inpatient PPS (IPPS), Outpatient PPS (OPPS), ASC Payment System, Clinical Lab Fee Schedule (CLFS), National Average Drug Acquisition Cost (NADAC). FY 2024 data. All publicly available from CMS.
Methodology: Facility rate applies when the procedure is performed in a hospital or ASC. Non-facility rate applies in a physician office. GPCI adjustments reflect regional cost-of-living differences.
This information is for educational purposes only and is not medical, financial, or legal advice. Actual costs depend on your insurance and provider. We recommend verifying costs directly with your provider. Full methodology · Terms of use